Japanese Ohsumi wins 2016 Nobel Prize in Physiology/Medicine

By Xuefei Chen Axelsson

Stockholm, Oct. 3(Greenpost)– Japan’s scientist Yoshinori Ohsumi has won the 2016 Nobel Prize in Physiology or Medicine, announced Thomas Perlmann, Secretary of the Nobel Committee in Medicine at Karalinska institute at the Nobel Forum in Karolinska Institute on Monday.

img_1765

“The Nobel Assembly at Karolinska Institute has today decided to award the 2016 Nobel Prize in Physiology or Medicine to Yoshinori Ohsumi for his discoveries of mechanisms for autophagy.”  said Perlmann.

img_1761

Nobel portrait.

 

 

img_1793 Professor Anna Wedell, Professor Nils-Göran Larsson and Maria Masucci  were present at the press conference. 

img_1781Committee member Professor Maria Macucci said Ohsumi’s discoveries led to a new paradigm in our understanding of how the cell recycles its content.

His discoveries opened the path to understanding the fundamental importance of autophagy in many physiological processes, such as in the adaptation to starvation or response to infection. Mutations in autophagy genes can cause disease and the autophagic process is involved in several conditions including cancer and neurological disease.

img_1789Ohsumi was born in 1945 in Fukuoka, Japan. He received his Ph. D from University of Tokyo in 1974. After spending three years at Rockefeller University, New York, USA, he returned to the University of Tokyo where he established his research group in 1988. He is since 2009 a professor at the Tokyo Institute of Technology.

thumb_dsc_3203_1024

Juleen Zierath, Chairman of the Nobel Committee was interviewed by Green Post. 

In an interview with Green Post, Juleen Zierath, Chairman of the Nobel Committee said Ohsumi’s discovery is very important because he showed that through starvation of cells, he found that the cells can recycle themselves and keep themselves alive even in a starvation status.

She said the discovery of autophagy mechanisms can lead to several conditions possibly including cancer and neurological disease treatment.

The Nobel Prize in Medicine this year is 8 million Swedish kronor or over one million US dollars. The prize will be issued on December 10.

The Nobel Prize in Physics will be announced tomorrow on Oct. 4 at the Royal Academy of Science.

今日头条:日本科学家大隅良典获2016诺贝尔生理学或医学奖

北欧绿色邮报网报道(记者陈雪霏)--2016诺贝尔医学奖3日正式出炉。

img_1765卡罗林斯卡医学院诺奖大会常务秘书托马斯.普尔曼在诺贝尔论坛大厅宣布,日本科学家大隅良典(Yoshinori Ohsumi)因其发现细胞自噬机制获得2016诺贝尔医学奖。 img_1781 卡罗林斯卡医学院教授马苏琪介绍说,自噬就是自己吃自己,就是说细胞可以通过自噬产生新细胞,新蛋白质。这样即使在饥饿状态下,细胞可以自噬坏死的或者受伤的细胞,从而保持生命的继续。

thumb_dsc_3203_1024卡罗林斯卡滋拉特(Zierath)教授在接受记者采访时说,这个发现非常重要,因为它向我们战士了细胞是可以循环再利用的。 这对将来应对饥饿,癌症和脑神经疾病都是非常有好处的。

img_1789大隅良典于1945年出生,今年71岁。他依然在做研究工作。他是1974年获得博士学位。1988年建立自己的实验室,专心研究蛋白质的退化。他通过饥饿细胞的方法发现细胞可以通过吃自己的不完善的细胞继续保持存活状态。1992年这个发现实现突破,并发表了论文。

img_1793后来,他还发现了自噬基因。发现这个机制对于癌症研究,糖尿病研究和神经系统的生理疾病研究都可能有很好的效果。

今天是今年的诺贝尔首个奖项出炉。明天将宣布物理奖,接着是化学,文学和和平奖。下周一宣布经济学奖。

img_1761今年奖金依然是800万克朗,但由于克朗的贬值,只约合93万美元了。

诺贝尔奖将在12月10日颁发。诺奖是从1901年开始颁发的。去年,中国科学家屠呦呦分享了诺贝尔医学奖。

图文/陈雪霏